Dimethocaine is a local anesthetic that, because of its similarity in action to cocaine, has potential for abuse. This compound completely inhibits dopamine uptake in rat striatal synaptosomes with an IC50 value of 1.2 µM comparable to that of cocaine (IC50 = 0.7 µM).1 As a result, dimethocaine dose-dependently substitutes for cocaine in drug discrimination tests in rats and rhesus monkeys.2,3 This product is intended for forensic and research purposes.
Formal Name 3-(diethylamino)-2,2-dimethyl-1-(4-aminobenzoate)-1-propanol, monohydrochloride
CAS Number 553-63-9
Molecular Formula C16H26N2O2 • HCl
Formula Weight 314.9
Formulation A crystalline solid
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